Power of Polyphenol Rich Sugarcane Extracts (PRSE’s) on improving the gut microbiome, mood, and blood work

Recruitment open

Aim of study

The study aims to evaluate the effects of polyphenol-rich sugarcane extract (PRSE) supplementation on health indicators and its influence on beneficial gut bacteria, blood biomarkers and overall well-being.

The study is a 6-month double-blinded randomised controlled study.

Eligibility criteria

Are aged 18-55 years of age
Currently live in Australia
Able to communicate fluently in English
Currently not lactating, pregnant or intending to become pregnant
A non-smoker
Do not consume more than 2 standard alcoholic drinks per day
Have no history of / do not currently suffer from heart disease, high blood pressure, diabetes, major GIT disorders or any other chronic disease or health concerns that may affect participant adherence to the trial as determined by investigators.
Are not taking any medication including frequent antibiotics and frequent non-steroidal anti-inflammatories (NSAIDs), herbal extracts, vitamin supplements or illicit substances and are committed to maintaining regime for the duration of the study.
Are committed to maintaining current diet and exercise regime from one week prior to study commencement and for the duration of the study.
Are not currently participating in any other health-related trials involving investigational or marketed products within 30 days prior to study commencement.
Willingness to comply with all requirements and procedures of the study.

Key points for participants

1. Supplementation of either a control sample (placebo) or a Polyphenol Rich Sugarcane Extract (PRSE) sample, twice a day (on in the morning and one in the evening) for a duration of 3 months, followed by the reversal of conditions for the subsequent months (for a total study duration of 6 months).

2. Completion of dietary, exercise and mood questionnaires at 3 time-points (baseline (start of the study), after the initial three months, and after the subsequent three months)

3. Faecal sample collection at 3 time-points (baseline (start of the study), after the initial three months, and after the subsequent three months).

4. Fingerpick blood sample at 3 time-points (baseline (start of the study), after the initial three months, and after the subsequent three months).

5. Completing a compliance survey via email at the end of each week (approximately 1-5 minutes in duration).

Reimbursement

Upon completion of the trial, you will be provided with a final report on your health markers (bloodwork and microbiome) valued at $1200 and a $50 supermarket gift voucher.